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Thread: Scientists Create Human-Pig Crossbreed

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    Scientists Create Human-Pig Crossbreed


    Scientists have created the first human-pig hybrid in a groundbreaking study that marks the first step in growing human organs inside animals.

    Named chimera, after the cross-species beast in Greek mythology, the pig-human embryos were created in the Salk Institute for Biological Studies in La Jolla, California and are the first hybrid made using two large, distantly-related species.

    “The ultimate goal is to grow functional and transplantable tissue or organs, but we are far away from that,” Juan Carlos Izpisua Belmonte, who led the project, said. “This is an important first step.”

    Human stem cells were injected into young pig embryos, which were then placed in surrogate cows. Of the more than 2,000 embryos, only 186 turned into chimeras – largely pig, with human elements in 1 out of 10,000 cells.

    After 28 days of a pig’s 112-day pregnancy, the pig-humans were removed as scientists say the embryos had developed enough for them to study in what way the cells mix together “without raising ethical concerns about mature chimeric animals,” Izpisua Belmonte said.

    As a pig’s gestation period of under four months is so much shorter than that of a human, the two species’ cells develop at different rates, providing a challenge for future chimera experiments.

    Even though a fully developed pig-human being born is a long way away, a chimera with human tissue can be used to study human disease and the differences in organs in differing species.

    Despite excitement surrounding the pig-human, concerns have been raised about the ethical implications of mixing human with animal.There is a worry that humanized animals, or animals with human brains could pose a threat to humanity.

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    Re: Scientists Create Human-Pig Crossbreed

    This is a valid topic even if it comes from a place like Daily Stormer.

    Personally, when it comes to this topic, I feel disturbed as an immediate gut reaction. Creating hybrids of two unrelated species is not something that should be allowed to happen. (I think we all already understand why, and no long explanations are necessary here.)

    They posit a weak excuse to create human-pig hybrids - that we may need replacement organs, and this hybrid species would exist to provide us with extra organs on demand. But there's several problems with that. Humans receiving these organs would still face transplant rejection issues the same way people who receive human to human organ transplants already do today. What difference would it make? Making them more readily available?
    The anti-rejection drugs also create considerable hardship for the people who take them as they are left with effectively zero immune system.

    Something far better would make organs more readily available, and that is growing organs from a patients own stem cells. This technology is already in progress, and it's far more promising than current Frankenstein experiments.

    Inspired by the regenerative abilities of an amphibian, Anthony Atala is driven to save lives by rebuilding organs.

    "Of the 4,000 Americans waiting for heart transplants, only 2,500 will receive new hearts in the next year. Even for those lucky enough to get a transplant, the biggest risk is the their bodies will reject the new heart and launch a massive immune reaction against the foreign cells. To combat the problems of organ shortage and decrease the chance that a patient’s body will reject it, researchers have been working to create synthetic organs from patients’ own cells. Now a team of scientists from Massachusetts General Hospital and Harvard Medical School has gotten one step closer, using adult skin cells to regenerate functional human heart tissue"

    "Around the world, there is a shortage of replacement organs. Some doctors see a possible solution: growing new organs from patients' own cells. Doctor Anthony Atala is director of the Institute for Regenerative Medicine at Wake Forest University in North Carolina."

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