Five highly informative X-chromosomal STRs in Koreans
Kyoung-Jin Shin1, 2, 3 , Byung-Ki Kwon2, 3, Sang-Seob Lee3, Ji-Eun Yoo1, Myung Jin Park1, Ukhee Chung1, Hwan Young Lee1, Gil-Ro Han2, 3, 4, Jong-Hoon Choi1, 3 and Chong-Youl Kim1, 3

(1) Department of Forensic Medicine, College of Medicine, Yonsei University, 134 Shinchon-Dong, Seodaemun-Gu, 120-752 Seoul, Korea
(2) Biometrics Engineering Research Center, Yonsei University, 134 Shinchon-Dong, Seodaemun-Gu, 120-749 Seoul, Korea
(3) Human Identification Research Institute, Yonsei University, 134 Shinchon-Dong, Seodaemun-Gu, 120-752 Seoul, Korea
(4) Department of Forensic Medicine, National Institute of Scientific Investigation, 331-1 Shinwol-Dong, Yangcheon-Gu, 158-707 Seoul , Korea

Received: 11 June 2003 Accepted: 29 October 2003 Published online: 22 November 2003

Abstract The five X-chromosomal short tandem repeats (STRs) GATA172D05, HPRTB, DXS8377, DXS101 and HumARA were analyzed in 150 males and 150 females from Korea. Markers were amplified in a quadruplex and a monoplex PCR reaction with fluorescently labeled primers. For accurate and reproducible STR typing, sequenced allelic ladders were constructed and a Genotyper macro was programmed. Some differences were found on comparing the allele frequencies of Koreans with those of other populations in DXS8377, DXS101 and HumARA. The forensic efficiency parameters showed that the five X-linked STRs are highly informative for forensic application in Koreans.