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Thread: mtDNA from the Neanderthal

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    Post mtDNA from the Neanderthal

    DNA sequence of the mitochondrial hypervariable region II from the neandertal type specimen.

    ...

    Proc Natl Acad Sci U S A. 1999 May 11;96(10):5581-5. Links


    DNA sequence of the mitochondrial hypervariable region II from the neandertal type specimen.

    Krings M, Geisert H, Schmitz RW, Krainitzki H, Paabo S.

    Max Planck Institute for Evolutionary Anthropology, Inselstrasse 22, D-04103 Leipzig, Germany.

    The DNA sequence of the second hypervariable region of the mitochondrial control region of the Neandertal type specimen, found in 1856 in central Europe, has been determined from 92 clones derived from eight overlapping amplifications performed from four independent extracts. When the reconstructed sequence is analyzed together with the previously determined DNA sequence from the first hypervariable region, the Neandertal mtDNA is found to fall outside a phylogenetic tree relating the mtDNAs of contemporary humans. The date of divergence between the mtDNAs of the Neandertal and contemporary humans is estimated to 465,000 years before the present, with confidence limits of 317,000 and 741,000 years. Taken together, the results support the concept that the Neandertal mtDNA evolved separately from that of modern humans for a substantial amount of time and lends no support to the idea that they contributed mtDNA to contemporary modern humans.

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    Post Re: mtDNA from the neandertal

    The divergence of the Neandertal mtDNA from the line
    leading to the contemporary human mtDNA gene pool is
    almost 3-fold older than the deepest divergence among contemporary
    human mtDNAs. The extent of sequence divergence
    exceeds that found within current chimpanzee subspecies.
    This shows that the Neandertal mtDNA and the human
    ancestral mtDNA gene pool have evolved as separate entities
    for a substantial period of time and gives no support to the
    notion that Neandertals should have contributed mtDNA to
    the modern human gene pool.
    Thats a direct contradiction to what Wolpoff and other multiregionalists said. They didnt use genetic data of course, and not even their morphological data is convincing.

    Seems to be a clear thing, not just with this, but also with the other studies, even on different subjects, which lead to similar conclusions.

    F.e.: http://www.forums.skadi.net/showthread.php?t=13796
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