http://www.timesonline.co.uk/article...330502,00.html
October 27, 2004
Gene tests prove that we are all the same under the skin
By Mark Henderson
Racists' central argument and theories linking intelligence to ethnic origin have been destroyed
THE popular notion that skin colour can indicate physical or mental differences between groups of people has been demolished by a new analysis of the human genome, which declares race to be a biologically meaningless concept.
Every human being shares more than 99.9 per cent of their DNA with everybody else, and the tiny variations that remain differ more within ethnic groups than between them, a major review of the evidence says.
NI_MPU('middle');It is impossible to look at people’s genetic code and deduce whether they are black, Caucasian or Asian, and there is no human population that fits the biological definition of a race, the study found.
Ethnicity is almost entirely socially and culturally constructed, and even the trait used most commonly to define it — skin colour — varies widely among people of similar ancestry.
The findings destroy the central argument of white supremacists and other racist groups, and refute controversial theories that attempt to link intelligence or criminality to ethnic origin.
Standard concepts of race, indeed, are so misleading that they are undermining efforts to untangle the true contribution that genetics make to individuality, and ought to be abandoned by science, the researchers said.
In medicine, for example, race is often used to predict whether patients will respond to particular drugs. While this can be true on average, it leads to generalisations that deny useful medicines to millions who do not meet ethnic stereotypes.
The results have emerged from a comprehensive survey of the science of human variation published today in a special issue of the prestigious journal Nature Genetics.
The research was organised by Howard University in Washington DC, a historically black college where most of the students and academics are African-American, and other contributors included Francis Collins, a leading architect of the Human Genome Project.
Charmaine Royal and Georgia Dunston of Howard University, who led the study, said that the mapping of the human genetic code had forced a “paradigm shift” on the science of race, in which old concepts and definitions were no longer up to the job.
“Existing biological models or paradigms of ‘racial’ and ‘ethnic’ categorisations cannot accommodate the uniqueness of the individual and universality of humankind that is evident in new knowledge emerging from human genome sequence variation research,” they said.
“The term ‘race’, as applied to humans, is incorrectly used. Traditional ‘racial’ designations in humans are not bounded, discrete categories but are fluid, socially defined constructs.”
The human genome map has shown that if two people of any ethnic origin are selected at random, only between 1 in 1,000 and 1 in 1,500 of their genes will differ. This makes our species among the most homogeneous known to science: populations of chimpanzees and fruit flies differ much more from one another in genetic terms. A typical Caucasian’s genes will be as similar — and as different — to those of another Caucasian as they will be to a black African or a Chinese person. About 90 per cent of genetic variation occurs within ethnic groups, rather than between them. Two Africans, though both superficially “black”, will differ more from one another than from other races. This reflects the course of evolution. Most scientists now accept that Homo sapiens emerged first in Africa, before a small group, perhaps numbering just a couple of hundred people, left about 40,000 years ago and spread through the rest of the world.
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