Tissue Antigens. 2003 May;61(5):384-92.


HLA alleles in isolated populations from North Spain: origin of the Basques and the ancient Iberians.

Sanchez-Velasco P, Gomez-Casado E, Martinez-Laso J, Moscoso J, Zamora J, Lowy E, Silvera C, Cemborain A, Leyva-Cobian F, Arnaiz-Villena A.

Department of Immunology and Molecular Biology, Hosp. 12 de Octubre, Universidad Complutense, Madrid, Spain.

HLA-A, -B, -DRB1, -DQA1 and -DQB1 alleles have been studied in three relatively isolated populations of northern Spain from Cantabria ( Pas Valleys inhabitants or Pasiegos and Cabuernigos) and from the Basque Country (Arratia Valley inhabitants). These populations have been compared with neighbouring ones and other Mediterraneans by using neighbour-joining dendrograms and plane genetic distances.